Disclosure profile

Who’s trading SYRE?

Spyre Therapeutics, Inc.

Every disclosed Congress and corporate-insider transaction in SYRE (Spyre Therapeutics, Inc.): 32 trades from 11 politicians and executives, each AI-scored. Updated as new filings land.

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FilerActionAmountFiledScore

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC 13GSell—2026-08-143

Albers Jeffrey W.SEC Form 4—$1.0M2026-08-105

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$1.9M2026-08-076

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$517k2026-08-075

Turtle CameronSEC Form 4Sell$849k2026-08-053

Burrows Scott LSEC Form 4—$1.1M2026-08-054

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$2.9M2026-08-036

Turtle CameronSEC Form 4Sell$1.1M2026-07-024

Sloan SheldonSEC Form 4—$929k2026-07-024

Burrows Scott LSEC Form 4—$105k2026-07-025

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$4.0M2026-07-016

Burrows Scott LSEC Form 4—$683k2026-06-266

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$1.3M2026-06-255

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy$399.7M2026-06-235

Fairmount Healthcare Fund II L.P.SEC Form 4—$400.4M2026-06-236

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC 13DSell—2026-06-236

HENDERSON MICHAEL THOMASSEC Form 4Sell$2.0M2026-06-235

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy—2026-06-224

Burrows Scott LSEC Form 4——2026-06-036

Turtle CameronSEC Form 4Sell—2026-06-034

Sloan SheldonSEC Form 4——2026-06-036

McKenna Mark C.SEC Form 4——2026-05-296

Albers Jeffrey W.SEC Form 4——2026-05-295

HENDERSON MICHAEL THOMASSEC Form 4——2026-05-294

Fairmount Healthcare Fund II L.P.SEC Form 4——2026-05-294

Stelzer LaurieSEC Form 4——2026-05-294

Milligan SandraSEC Form 4——2026-05-294

Spyre Therapeutics, Inc. (SYRE)SEC 8-K——2026-05-295

HENDERSON MICHAEL THOMASSEC Form 4Sell—2026-05-086

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy—2026-05-016

Spyre Therapeutics, Inc. (SYRE) (CIK 0001636282)SEC Form 144Buy—2026-05-015

Public-record disclosures (SEC Form 4 & Congressional PTRs). Research tool, not investment advice.